NOBARF Oral Disintegrating Strips 1's
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Introduction About NOBARF ORAL DISINTEGRATING STRIPS
NOBARF ORAL DISINTEGRATING STRIPS contains Ondansetron, which belongs to a group of medicines called Anti-emetics. It is used to manage nausea and vomiting induced by chemotherapy or radiotherapy. NOBARF ORAL DISINTEGRATING STRIPS is also used after surgeries (operation) to manage nausea and vomiting.
Before taking NOBARF ORAL DISINTEGRATING STRIPS, inform your doctor if you have severe constipation, heart or liver problems, imbalance with the levels of salts in the blood, such as potassium, sodium and magnesium or if you have been scheduled for any surgery.
NOBARF ORAL DISINTEGRATING STRIPS is not recommended for use during pregnancy. This medicine may pass through the breast milk hence it is not recommended during breastfeeding. Consult your doctor before taking this medicine.
The dose of NOBARF ORAL DISINTEGRATING STRIPS will depends on the age, body weight and disease condition of your child. Dosage adjustment is not required in elderly patients, hence consult your doctor before taking NOBARF ORAL DISINTEGRATING STRIPS.
The most common side effects of taking NOBARF ORAL DISINTEGRATING STRIPS includes headache, flushing and constipation. Consult your doctor if any of these above symptoms gets worse.
Uses Of NOBARF ORAL DISINTEGRATING STRIPS
- Used to manage nausea and vomiting induced by chemotherapy, radiotherapy and surgery
How NOBARF ORAL DISINTEGRATING STRIPS Works
NOBARF ORAL DISINTEGRATING STRIPS is a serotonin 5-HT3 receptor antagonist (specific chemical receptor) which works by blocking serotonin receptors in CTZ chemoreceptor trigger zone (zone in the brain that is responsible for causing nausea and vomiting).
How to use NOBARF ORAL DISINTEGRATING STRIPS
Always use NOBARF ORAL DISINTEGRATING STRIPS as advised by your physician. Do not handle the medicine with wet hands. Put it in your mouth and do not swallow it. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects Of NOBARF ORAL DISINTEGRATING STRIPS
Common
- headache
- flushing (feeling of warmth)
- constipation
Uncommon
- uncontrolled body movements along with upward rolling movement of the eyeballs
- fits (seizures)
- irregular heartbeat (fast or slow)
- chest pain
- fainting or feeling dizzy (low blood pressure)
- hiccups
Rare
- visual disturbances like blurred vision
- effects of heart rhythms resulting in feeling lightheaded or loss of consciousness
Stop taking NOBARF ORAL DISINTEGRATING STRIPS and contact your doctor if you experience any of the following side effects:
- sudden wheezing and chest pain or tightness
- swelling of eyelids, face, lips, mouth or tongue
- skin rash, red spots or lumps under your skin (hives) or anywhere on the body
How To Manage Side Effects
Headache:
Take rest. Have good amount of sleep. Have a balanced diet and at regular intervals. Add more fluids to your diet. Drink plenty of water to replenish water stores.
Constipation:
Eat plenty of fibre rich foods such as fresh fruits, vegetables, and cereals. Drink water and exercise regularly. Contact your doctor if constipation persists.
Dizziness:
Lie down until the dizziness passes and get up slowly. Do not bend down suddenly. Get a lot of rest. Walk slowly and carefully. Take plenty of fluids. Avoid drinking coffee, alcohol, or smoking. Consult your doctor if the condition persists for long or gets worsened.
Warning & Precautions
Pregnancy
NOBARF ORAL DISINTEGRATING STRIPS is generally not recommended for use during pregnancy unless considered clearly necessary. Consult your doctor before taking NOBARF ORAL DISINTEGRATING STRIPS.
Breastfeeding
NOBARF ORAL DISINTEGRATING STRIPS is not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking NOBARF ORAL DISINTEGRATING STRIPS.
Driving and Using Machines
Do not drive or operate any machines if you feel dizzy or uneasy after taking NOBARF ORAL DISINTEGRATING STRIPS.
Liver
NOBARF ORAL DISINTEGRATING STRIPS should be used with caution in patients with liver problems. Consult your doctor before taking NOBARF ORAL DISINTEGRATING STRIPS.
Allergy
Do not take NOBARF ORAL DISINTEGRATING STRIPS if you are allergic to Ondansetron, granisetron or palonosetron or to any other ingredients of this medicine.
Heart Disease
NOBARF ORAL DISINTEGRATING STRIPS should be used with caution in patients with heart diseases such as uneven heartbeats (arrhythmias) or congestive heart failure. Consult your doctor before taking NOBARF ORAL DISINTEGRATING STRIPS.
Others
Before taking NOBARF ORAL DISINTEGRATING STRIPS, inform your doctor if you:
- have a blockage in your gut
- have problems with the levels of salts in the blood (such as potassium, sodium and magnesium)
- are intolerant to some sugars (Ex. lactose intolerance)
Use in pediatrics:
Your doctor will give the right dose of NOBARF ORAL DISINTEGRATING STRIPS depends on your child’s age, body weight and disease condition. Consult your doctor before taking NOBARF ORAL DISINTEGRATING STRIPS.
Use in geriatrics:
Dosage adjustment is not required in elderly patients, hence consult your doctor before taking NOBARF ORAL DISINTEGRATING STRIPS.
Interactions
A. Drug-Drug Interactions:
Before taking NOBARF ORAL DISINTEGRATING STRIPS, inform your doctor, if you are taking any of the following medicine:
- apomorphine (used to manage Parkinson’s disease)
- medicines used to manage epilepsy (Ex. phenytoin, carbamazepine)
- medicines used to manage lung infections like Tuberculosis (Ex. rifampicin)
- tramadol, methadone (medicine used to provide relief from pain)
- medicines used for psychotic disorders (Ex. haloperidol)
- medicines used to manage heart problems such as abnormal heart beats (Ex. amiodarone) and/or high blood pressure (Ex. atenolol, timolol)
- cancer medicines (Ex. doxorubicin, daunorubicin, monoclonal, trastuzumab)
- erythromycin, ketoconazole (used to manage infections)
- medicines used to manage depression and anxiety (ex. fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram, venlafaxine, duloxetine escitalopram)
Overdosage:
If you or anyone else accidentally takes too much of NOBARF ORAL DISINTEGRATING STRIPS, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Ondansetron |
| Pharmacological Category | : | Serotonin antagonist |
| Therapeutic Indication | : | Nausea and Vomiting in patients (undergoing chemotherapy, radiotherapy, surgery) |
| Dosage Forms | : | Tablet, Injection, Dispersible Tablet, Syrup, Suspension, Oral strips, Lozenges, Pastille |
More Information
- Keep the medicine out of reach in children
- Store NOBARF ORAL DISINTEGRATING STRIPS at room temperature
FAQs About NOBARF ORAL DISINTEGRATING STRIPS
Q: Is NOBARF ORAL DISINTEGRATING STRIPS a chemo drug?
A: No, it is not a chemo drug. It belongs to a group of medicines called serotonin antagonists and used to manage side effects caused due to chemotherapy.
Q: Is NOBARF ORAL DISINTEGRATING STRIPS safe in pregnancy?
A: NOBARF ORAL DISINTEGRATING STRIPS is not recommended for use in pregnancy unless clearly necessary as it is not known whether it may cause harm to the unborn baby. Contact your doctor before taking.
Q: What NOBARF ORAL DISINTEGRATING STRIPS is used for?
A: NOBARF ORAL DISINTEGRATING STRIPS is used to manage nausea and vomiting caused by medical managements like chemotherapy, radiotherapy or surgery.
Q: For how long should you take NOBARF ORAL DISINTEGRATING STRIPS?
A: Your doctor will advise you on how long you should continue to take NOBARF ORAL DISINTEGRATING STRIPS. Consult your doctor from time to time to review your management and assess your symptoms.
Q: What happens if you take more NOBARF ORAL DISINTEGRATING STRIPS than your required dose?
A: If you or anyone else accidentally takes too much of NOBARF ORAL DISINTEGRATING STRIPS, consult your doctor immediately or visit the nearby hospital.
Q: What side effects are seen with NOBARF ORAL DISINTEGRATING STRIPS?
A: The most common side effects of taking NOBARF ORAL DISINTEGRATING STRIPS are headaches, flushing (feeling of warmth), constipation. Consult your doctor if above side effects got worse.
References
1. KD. Tripathi. Section 11, Gastrointestinal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 661.
2. LTS Lohmann Therapie-Systeme AG Lohmannstrasse. Andernach GERMANY [Revised April 2022] [Accessed on 29 September 2022] https://www.medicines.org.uk/emc/files/pil.9595.pdf
3. Koland M, Sandeep V, Charyulu N. Fast Dissolving Sublingual Films of Ondansetron Hydrochloride: Effect of Additives on in vitro Drug Release and Mucosal Permeation. J Young Pharm. 2010 Jul;2(3):216-22. [Accessed on 29 September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964757/
4. Kumria R, Gupta V, Bansal S, Wadhwa J, Nair AB. Oral buccoadhesive films of ondansetron: Development and evaluation. Int J Pharm Investig. 2013 Apr;3(2):112-8. [Accessed on 29 September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757901/
5. Ondansetron Soluble Films. [Accessed on 29 September 2022] https://my.clevelandclinic.org/health/drugs/20819-ondansetron-soluble-films
6. Myoclinic. [Accessed on 29 September 2022] https://www.mayoclinic.org/drugs-supplements/ondansetron-oral-route-oromucosal-route/proper-use/drg-20074421
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